Prednisolone-like Action of Sinomenine Injected into Joint Cavity

Absorption of hydrocortisone from the joint cavity into the circulation.

Intra-articular hydrocortisone therapy has been in extensive use for approximately 5 years. It has been stated that this therapy is strictly for local palliation and has no systemic effects (Hollander, 1953). Local hydrocortisone therapy is especially recommended in cases in which the systemic use of cortisone is contra-indicated on general medical grounds (Kersley, 1953). On the other hand, Yo...

Electrolyte and Volume Changes in Fluids Injected into the Peritoneal Cavity *

Theexperiments here presented were planned to permit a study of the qualitative and quantitative changes that take place in certain types of fluids which are often injected into the peritoneal cavity or subcutaneous tissues for therapeutic purposes. Data were obtained which show the alterations in the electrolyte pattern and in the volume which occur during the process of absorption from the pe...

Secretion of prednisolone into breast milk.

The secretion of 3H in the breast milk of seven volunteers was studied over a period of about 48 hours after the oral administration of 5 mg of 3H-prednisolone. A range of 0.07 to 0.23% of the dose per litre was recovered.

The Sustained Action of Erythropoietin Injected Repeatedly into Rats and Mice.

Anxiolytic-like effect of losartan injected into amygdala of the acutely stressed rats.

It has been recognized that the stress-related peptides are involved in anxiety states. Angiotensin II receptor blockade by systemic administration of the AT(1) receptor antagonists has been proposed as a new treatment possibility for anxiety disorders. For better understanding of the related mechanisms, in this study we evaluated effects of bilateral intraamygdaloid injections of 2 (LOS 2) and...